Tutorial


1. Determine if a Gene of Interest is a Cancer Driver Gene

Click on the Search menu option to reach the Search page.

Search

Select “All cancers” or any specific cancers in the Cancer field.

cancer

You can use Control-click (PC) or Command-click (Mac) to select multiple menu options.

cancer

You can use Shift-click to select a range of menu options.

cancer

Select “All studies” or any specific studies in the Study field.

cancer

You can use Control-click (PC) or Command-click (Mac) to select multiple menu options.

cancer

You can use Shift-click to select a range of menu options.

cancer

Enter a gene symbol or gene ID in the Gene field (e.g., "PTEN").

gene

You can use “*” as a wildcard character at the end of a partial word (e.g., “P*”).

gene

You can use “-” to exclude a term from search results (e.g, "-PARD3")

gene

You can enter multiple genes, separating each with a single space. You can copy and paste lists of genes into the Gene field from other programs such as an Excel spreadsheet. Note that your browser may respond slowly if you enter hundreds of thousands of characters.

gene

Select an organism beneath the Gene field that corresponds with the gene symbol or gene ID you have entered.

organism

Select “ID” or “symbol” beneath the Gene field to specify whether your entry in the Gene field corresponds with a gene ID or a gene symbol.

identifier

Click on Search.

search

The CCGD will return a results page listing every study that identified the gene as a candidate driver. If the CCGD did not recognize the gene you entered, the results page will include a red warning box.

search results

If you want to download a copy of search results, click on the Export button.

export

You will have the option of downloading a .BED file for a genome viewer or a .CSV file that can be opened in Excel.

export  export

Click on a gene symbol or table row to obtain more detailed information.

gene symbol

The CCGD will return a page with many hyperlinks for your convenience.

gene detail

2. Determine Cancer Driver Genes in a Cancer of Interest

Click on the Search menu option to reach the Search page.

Search

Select “All cancers” or any specific cancers in the Cancer field.

cancer

You can use Control-click (PC) or Command-click (Mac) to select multiple menu options.

cancer

You can use Shift-click to select a range of menu options.

cancer

Select “All studies” or any specific studies in the Study field.

cancer

You can use Control-click (PC) or Command-click (Mac) to select multiple menu options.

cancer

You can use Shift-click to select a range of menu options.

cancer

Leave the Gene field blank. Note that the fields below the Gene field will be ignored.

gene

Click on Search.

search

The CCGD will return a results page listing every study that identified the gene as a candidate driver. If the CCGD did not recognize the gene you entered, the results page will include a red warning box.

search results

If you want to download a copy of search results, click on the Export button.

export

You will have the option of downloading a .BED file for a genome viewer or a .CSV file that can be opened in Excel.

export  export

Click on a gene symbol or table row to obtain more detailed information.

gene symbol

The CCGD will return a page with many hyperlinks for your convenience.

gene detail

3. Determine Cancer Driver Genes in a Study of Interest

Click on the Search menu option to reach the Search page.

Search

Select “All cancers” or any specific cancers in the Cancer field.

cancer

You can use Control-click (PC) or Command-click (Mac) to select multiple menu options.

cancer

You can use Shift-click to select a range of menu options.

cancer

Select “All studies” or any specific studies in the Study field.

cancer

You can use Control-click (PC) or Command-click (Mac) to select multiple menu options.

cancer

You can use Shift-click to select a range of menu options.

cancer

Leave the Gene field blank. Note that the fields below the Gene field will be ignored.

gene

Click on Search.

search

The CCGD will return a results page listing every study that identified the gene as a candidate driver. If the CCGD did not recognize the gene you entered, the results page will include a red warning box.

search results

If you want to download a copy of search results, click on the Export button.

export

You will have the option of downloading a .BED file for a genome viewer or a .CSV file that can be opened in Excel.

export  export

Click on a gene symbol or table row to obtain more detailed information.

gene symbol

The CCGD will return a page with many hyperlinks for your convenience.

gene detail